Historical and contemporary DNA indicate fisher decline and isolation occurred prior to the European settlement of California.

Establishing if species contractions were the result of natural phenomena or human induced landscape changes is essential for managing natural populations.Fishers (Martes pennanti) in California occur in two geographically and genetically isolated populations in the northwestern mountains and southern Sierra Nevada.Their isolation is hypothesized t

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Modulation of calcium-binding proteins expression and cisplatin chemosensitivity by calcium chelation in human breast cancer MCF-7 cells

Cisplatin (CDDP) is currently one of the most effective FDA-approved treatments for breast cancer.Previous studies have shown that CDDP-induced cell Wine Cabinets death in human breast cancer (MCF-7) cells is associated with disruption of calcium homeostasis.However, whether the sensitivity of breast cancer cells to cisplatin is associated with dys

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